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Review of Neurontin (Gabapentin)

Gabapentin

Neurontin is a medicine based on the active substance Gabapentin. Gabapentin is is a pharmaceutical medicine that was originally developed for the treatment of epilepsy, but currently it is widely used to relieve pain, neuropathic pain, however in combined therapy of epilepsy.

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Pharmaceutical form of Neurontin (Gabapentin)

Capsules

Neurontin (Gabapentin) is supplied in a form of capsules by 100 mg, 300 mg or 400 mg of Gabapentin.Capsules also contain lactose monohydrate, maize starch, talc, gelatin, purified water, and sodium lauryl sulphate.

Dosage of Neurontin and special recommendations

For the treatment of postherpetic neuralgia in adults, the following daily (Gabapentin) Dosages is prescribed:

  • A single 300MG dose of Neurontin on Day 1
  • 600 MG /day on Day 2 (divided in 2 intakes)
  • 900MG day on Day 3 (divided in 3 intakes)
If the effect of Neurontin is insufficient, the daily dose may be gradually increased to 1800 mg (divided in 3 intakes).

Clinical studies show that the most effective and optimal daily dosage is 1800 mg daily, doses exceeding this amount do not show improvement of the effect achieved by the daily dose of 1800 mg.

For the treatment of epilepsy, Neurontin is used in different doses for children over 3 years and for adults, the daily dose of Neurontin for adults and children over 12 years is: from 900 to 1800 mg/day taken in divided doses (three times a day), using 300 or 400 mg capsules, or 600 or 800 mg tablets. The starting dose is 300 mg three times a day.

If necessary, the daily dose may be increased using 300 or 400 mg capsules, or 600 or 800 mg tablets three times a day up to 1800 mg/day. The interval between the previous dose and increased dose should be no less than 12 hours.

Patients with diabetes and acute renal failure should take reduced doses of Neurontin.

Contraindications for Neurontin (Gabapentin) use:

Neurontin is contraindicated to:

  • children under 3 years
  • people suffering from pancreatitis
  • people suffering from generalized epileptic seizures.

If you experience some of these side effects, or some other side effects, you should reduce the daily dose and consult your doctor right away.